Add Aortic Aneurysm to the List of Quinolone Concerns

February 2019

Risk of aortic dissection, rupture, or aneurysm is leading FDA to require added warnings on oral and injectable quinolone labels.

These aortic complications are rare...occurring in about one in every 11,000 patients in the general population each year.

But that number can jump to one in about 300 high-risk patients. This includes the elderly...patients with a history of aneurysm, hypertension, vascular disease, or smoking...or those with genetic disorders such as Marfan syndrome or Ehlers-Danlos syndrome.

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